An interesting example of the persistence of a theory that for all practical purposes has seen its rise and fall, is furnished by the case of uric acid. No matter how abundantly the results of reliable research are published, nor how carefully the leading clinicians controvert the mistaken ideas of a previous generation, a large proportion of the unprogressive will cling to the most worn-out theory or system for no better reason than that the idea once secured a firm place in their mental armamentarium, and that it would require an effort to dislodge it. A student is told that uric acid accumulates in the blood and leads to all sorts of diseases, and that uric acid in the urine means an excess of uric acid in the blood; if he is of a certain type, for the rest of his life a "brick dust" deposit in a urinal calls
URIC-ACID THEORIES. JAMA. 1904;XLIII(8):550–551. doi:10.1001/jama.1904.02500080028003
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