The significance of the changes in the white corpuscles which occur in appendicitis has of recent years been the source of a great deal of discussion, and a perusal of the proceedings of the various medical societies shows that on the one hand there are those who consider the leucocyte count of little or no value, and on the other those who perhaps pin too much faith on it. The differences of opinion are so great that it seems hard to explain them. Several factors are doubtless at work to cause the disagreement. Among the more important of these must be mentioned the basing of opinion on an insufficient number of cases, too infrequent blood examinations, and the tendency to regard the blood examination as a specific diagnostic point rather than to consider it as a link in the diagnostic chain. The ground has recently been worked over by
THE VALUE OF THE LEUCOCYTE COUNT IN APPENDICITIS. JAMA. 1904;XLIII(8):553. doi:10.1001/jama.1904.02500080031010
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