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Article
September 24, 1904

NATURAL AND ARTIFICIAL ANTHRAX IMMUNITY.

JAMA. 1904;XLIII(13):895-896. doi:10.1001/jama.1904.02500130043007
Abstract

The study of immunity and susceptibility to disease, by test-tube experiments, has brought to light a number of seemingly paradoxical results. It has been shown for instance, that human blood serum is strongly bactericidal in vitro for typhoid and dysentery bacilli and that it may retain this property, although sometimes in a less degree, during the course of these diseases. Chickens and swine are practically immune to anthrax infection, and yet it is found that the blood and the blood serum of these animals form good culture media for anthrax bacilli. Dogs also are relatively immune, and their blood likewise is a good nutritive medium for this form of micro-organism. Rabbits, on the other hand, are very susceptible to anthrax infection, while their extravascular blood serum almost instantly kills large numbers of the bacilli. Cattle and sheep are susceptible to anthrax, and their blood serum also forms good culture medium,

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