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October 1, 1904


JAMA. 1904;XLIII(14):980-981. doi:10.1001/jama.1904.92500140001l

Splenic anemia is a distinct variety of anemia, and entirely different from the various conditions characterized by enlargement of the spleen and classified under various names. The distinctive features are enlargement of the spleen without enlarged lymphatics, evidence of pigmentary deposits, and if long continued, disturbance of the liver and ascites. So far as etiology is concerned, nothing definite is known.

The special features of the condition are: 1, Slight diminution in the number of red corpuscles; 2, reduction in hemoglobin, and 3, a most remarkable reduction in leucocytes. This last seems to be the pathognomonic condition.

H. C. Wood1 first described this in 1871. He says: "I now desire to show that there is still a third form of pseudoleukemia, a splenic variety. Under the names of tumor of the spleen, splenic cachexia, etc., medical records furnish accounts of cases which 1

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