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October 15, 1904


JAMA. 1904;XLIII(16):1145. doi:10.1001/jama.1904.92500160002a

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Patient.  —Mrs. W., aged 79, called me at 7 p. m., August 24.

History.  —I learned that at 10 a. m. she had applied a belladonna plaster 5x7½ inches over the lumbar spine. During the afternoon her face became flushed and there was a blue discoloration of the lips. She experienced difficulty in swallowing and complained of vertigo and dryness of the mouth. She had taken a dose of Paine's Celery Compound, and to this she attributed her symptoms.

Examination.  —There was active delirium, restlessness, rigidity of the flexor muscles, carphologia, bounding pulse (102), temperature 100 F., difficult articulation and extremely dilated pupils.

Treatment.  —Pilocarpin nitrate, gr. ⅛, was given hypodermically at once, and the belladonna plaster was removed; and after an hour morphin gr. ¼, with pilocarpin gr. ⅛, was given hypodermically.

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