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The symptomatology of tuberculous meningitis when well inaugurated is certainly characteristic and can offer very few difficulties to those who have followed any number of these cases through an illness. There has always been, however, a desire on the part of clinicians to recognize the disease in its incipient stage, or as the books call it, the first stage of the disease. So important a matter is this to the practitioner that the consultant is often confronted in his daily work with the important problem as to whether a certain symptom complex can definitely be said to be indicative of tuberculous meningitis. There was a discussion of this matter in a meeting of the Pediatric Society in 1890. At this time stress was laid on the fact that the early diagnosis of tuberculous meningitis was not only difficult, but in some cases well nigh impossible. Such symptoms as persistent vomiting,
KOPLIK H. THE CLINICAL HISTORY AND RECOGNITION OF TUBERCULOUS MENINGITIS.. JAMA. 1907;XLVIII(14):1149–1154. doi:10.1001/jama.1907.25220400001001
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