Since the publication, in August, 1903, of Senn's report of a case of leukemia treated with the x-rays, the number of recorded cases has been increasing weekly. In March, 1904, at the time that Brown1 published the second recorded case, we commented editorially on the subject, mentioning the fact that the way in which the rays acted was obscure, and suggesting conservatism in drawing conclusions as to the permanent effect of this form of treatment. The publication of the numerous cases above mentioned and the accumulation of certain scientific data make it worth while to draw attention to this subject once more.
The experimental work of Heineke2 seems to throw some light on the modus operandi of the x-ray in leukemia cases. This author shows that the exposure of certain of the lower animals to the action of the x-rays leads to definite changes which
THE ACTION OF THE X-RAYS IN LEUKEMIA. JAMA. 1904;XLIII(20):1470–1471. doi:10.1001/jama.1904.02500200040002
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