In two cases I have had the opportunity of observing, a systolic murmur, not previously present, was heard during or soon after an attack of biliary colic. The first case was in a woman, a doctor's mother, sixty-one years of age, who had had her first attack of gallstone colic eighteen years before. I saw her in a typical seizure, the third within a few days, as a sequel to which she passed five faceted stones. At the first examination I discovered a loud, systolic murmur at the apex, which the doctor assured me had not been present before. There was no accentuation of the second pulmonic sound. The murmur persisted for nine days; the jaundice, which was pronounced, lasted only four days. After an interval of two years, during which the patient was very well, she had another attack of biliary colic with jaundice, but without murmur, and without
RIESMAN D. THE DEVELOPMENT OF CARDIAC MURMURS DURING ATTACKS OF BILIARY COLIC. JAMA. 1907;XLVIII(19):1589–1590. doi:10.1001/jama.1907.25220450033002g
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