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November 26, 1904


JAMA. 1904;XLIII(22):1630. doi:10.1001/jama.1904.92500220002a

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A man, aged 26, English, bricklayer by occupation, has had rheumatism at varying intervals since he was 15 years old. His father is in good health, but drinks a good deal. Mother is extremely "nervous." The patient complained of lameness and rheumatic pains which had persisted for the last four months. The right shoulder, wrist, knee and ankle joints were swollen and painful. Temperature was 103, pulse 96. His tongue was heavily coated and his breath bad. He complained of headache. The urine was of dark red color, high specific gravity and acid in reaction. Calomel and saline cathartics were given to clean out the intestinal tract. As the usual anti-rheumatic remedies failed to give relief and anodynes seemed to have no effect on the pain, venesection was performed and about twelve ounces of blood were withdrawn. Following this, two pints of normal salt solution were injected beneath the skin of the breasts. All pain (except a slight soreness) had

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