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December 3, 1904


JAMA. 1904;XLIII(23):1696-1700. doi:10.1001/jama.1904.92500230001g

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There is a condition found in new-born babies, and usually confounded with sepsis neonatorum, which seems to me to be entirely autotoxic in character. This condition is often manifested on the first day of life, but may be delayed two or three days. The symptoms are vomiting, cardiac depression, poor circulation, frequently cyanosis, irregular and weak respiration, convulsions in the severer cases, and special symptoms on the part of the bowels and skin. The stools, which are generally frequent, do not become yellow, but remain green, and contain considerable mucus. A peculiar skin eruption appears about the third day, but may be delayed for a week or even more. This eruption consists of pustules, so small that their pustular character is often overlooked. These pustules are located principally on the upper portion of the chest, the neck and chin, and in the bends of the elbows. About each pustule is

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