It was long maintained that an antagonism exists between valvular disease of the heart and pulmonary tuberculosis by reason of the increased amount of blood present in the lungs as a result of stasis, although the view did not remain undisputed. As a matter of fact, however, the coincidence of the two conditions, while it does occur, is not altogether common. It has also been contended that pulmonary tuberculosis develops especially in individuals with small hearts, cardiac enlargement when present being attributed to complicating conditions.
With the view of studying the frequency and relationship of tuberculous lesions of the lungs, pleura, pericardium, heart and great vessels, Dr. George W. Norris1 analyzed 7,040 postmortem records in three Philadelphia hospitals. Among this number there were 1,764 cases of tuberculosis of various kinds. Tuberculosis of the lungs was found so frequently in association with valvular disease of the heart that the conclusion
THE RELATIONS BETWEEN PULMONARY TUBERCULOSIS AND VALVULAR DISEASE OF THE HEART.. JAMA. 1904;XLIII(23):1704–1705. doi:10.1001/jama.1904.02500230034007
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