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January 28, 1905


JAMA. 1905;XLIV(4):297-298. doi:10.1001/jama.1905.02500310041005

The large amount of study which has been devoted to the spleen in the last few years has led to a reclassification of splenic diseases. The association of certain forms of splenomegaly with hyperglobulia, and of other forms with anemia has been well emphasized in recent literature. Some writers have classed with splenic anemia certain cases of icterus associated with enlargement of the spleen, which recent study teaches belong in a class by themselves. According to von Krannhals,2 who has quite recently collected all of the published cases, the association of congenital icterus with chronic spleen tumor was first noted by Minkowski in 1900. One writer has remarked "the new things in medicine are the things which have been forgotten," and von Krannhals has overlooked the fact that similar cases were reported by Claude Wilson2 as early as 1890.

The disease seems to be one which must be