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October 25, 1890

The Disease of the Skin called Paget's Disease.

JAMA. 1890;XV(17):627. doi:10.1001/jama.1890.02410430035014

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Maladie de la Peandite Maladie de Paget, par Dr. Louis Wickham. Paris: G. Masson, 1890.

In 1874 Sir James Paget described the peculiar inflammation of the nipple and areola of the breast that preceded the development of cancer. This condition has since been called malignant papillary dermatitis. It remained, however, for Darier (Sur une forme de psorospermose, ou maladie de Paget. Société de Biologie, April 13, 1889) to demonstrate the parasitic nature of the affection. He has also contributed several important chapters to this monograph.

The work opens with a definition of Paget's disease, which is said to be a parasitic affection,belonging to the group of cutaneous psorospermes, characterized by chronic inflammation of the skin, its glands, and their ducts, followed by epithelial proliferation. Up to the present this disease has been considered a special affection of the breast and mammæ, but other regions may be affected; there is recorded

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