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The antiseptic value of drugs in the treatment of phthisis is well recognized by the profession. But how to administer them in sufficient strength and quantity to control the tubercular and septic processes has been the problem. If administered by the stomach in sufficient strength and quantity to properly saturate the lungs, the stomach and lower alimentary tract is so irritated that the digestive function is greatly deranged. Hence nature's method of controlling the disease by vital resistance is much impaired.
If introduced directly into the lungs by parenchymatous injection, so much irritation is produced that an exudate is thrown out which occludes the finer air passages preventing the introduction of the medicaments.
For two years I have had the medical direction of the Cook County, Illinois, institution. During this period I have treated a great many cases of pulmonary tuberculosis and have always given the patients the benefit of
JOHNSON GW. A REPORT OF THE TREATMENT OF PULMONARY TUBERCULOSIS BY THE INHALATION OF ANTISEPTIC VAPORS. JAMA. 1898;XXX(6):315–317. doi:10.1001/jama.1898.72440580031001g
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