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January 17, 1891


JAMA. 1891;XVI(3):92-96. doi:10.1001/jama.1891.02410550020004

Therapeutics and Pharmacology. 

Salicylic Acid for the Prevention of Scarlet Fever.  —In the Centralblattfür klinische Medicin, for October, are quoted by Dr. G. Sticker, some of the clinical experiences of Dr. G. de Rosa, an Italian physican, in an effort to curtail an epidemic of scarlet fever by the internal administration of salicylic acid. Out of sixty-six children exposed to infection—twenty-seven patients being down with the disease in the same building—only three contracted the fever, after the salicylic plan of treatment had been put into operation, and in these three cases, the failure was ascribed to the fact that there had probably been a longer exposure to the infection than in the other set of cases. It is recommended that the drug should be given promptly after there has been danger of infection, the dose being one to five grains daily until the exposure has passed by. Isolation is not