The hopelessness of pyloric cancer, or, indeed, of any form of gastric cancer when the diagnosis has become so plain that "he who runs may read," and the possibility of affording prolonged or even permanent relief if timely surgical interference could be advised, makes its early diagnosis of paramount importance. Unfortunately, it is one of the most difficult chapters in internal medicine, and it must be confessed that we are to-day without a single pathognomonic sign of early pyloric or other gastric cancer. The fact is that in most cases of gastric cancer, as in many other chronic diseases, the initial stages are practically symptomless. Symptoms, however, usually supervene at a comparatively early stage, and many of these cases would have a possible chance for more or less successful surgical treatment if these symptoms were given proper consideration and the patient placed under the care and treatment of a physician skilled in gastric disorders.
McCASKEY GW. EARLY DIAGNOSIS AND OPERATIVE TREATMENT OF GASTRIC CANCER.. JAMA. 1905;XLIV(13):1026–1029. doi:10.1001/jama.1905.92500400030001d
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