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February 28, 1891


JAMA. 1891;XVI(9):310-311. doi:10.1001/jama.1891.02410610022004

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Lépine, in a paper before the International Medical Congress, on "The Treatment of Bright's Disease," maintained that the chief indication was the prevention of uræmia. With this end in view he laid special stress upon the importance of lessening nitrogenous food to a point where tissue waste would be just balanced, which he placed at about 80 grams of albumen daily for the average adult. In practice he thinks the best results will be achieved by a milk diet, to which a certain proportion of carbo-hydrates are added, as the nitrogenized constituents are present in too great relative proportion in milk.

If we adopt the view that " uræmia " is dependent upon an excess of urea in the blood (Willis), or of carbonate of ammonia (Frerichs), or of creatin and creatinine (Oppler, Perls and Zalesky), it is at once apparent that a lessening of the proteids of the diet would decrease

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