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Article
February 19, 1898

DISEASES ASSOCIATED WITH PERSISTENCE AND ENLARGEMENT OF THE THYMUS GLAND AND GENERAL LYMPHATIC HYPERPLASIA.

JAMA. 1898;XXX(8):441-442. doi:10.1001/jama.1898.02440600041008
Abstract

In the recent Bulletin of the Ohio Hospital for Epileptics, at Gallipolis, Ohio, Dr. A. P. Ohlmacher, the Director of the Pathological Laboratory, describes postmortem examinations in certain cases of epilepsy. In three of the five cases examined there was found a persistent, enlarged thymus, and in four of the cases there was a more or less general lymphadenoid hyperplasia. On this account he calls attention to the other conditions that frequently occur in connection with thymic enlargements, namely: 1, so-called thymic asthma; 2, sudden death in adults with persistent thymus; and 3, exophthalmic goiter.

Thymic asthma is the laryngismus stridulus of the English and American clinicians. Its anatomic basis has given rise to much discussion in German literature; the strife has concerned especially the relationship of the enlarged thymus usually present to the affection, and the controversy is still unended. Thymic asthma or laryngismus stridulus is usually a benign

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