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February 19, 1898

A Correction of Dr. Charles Denison's Article: " The Antitoxic Treatment of Tuberculosis."

JAMA. 1898;XXX(8):446. doi:10.1001/jama.1898.02440600046015

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Chicago, Feb. 14, 1898.

To the Editor:  —Dr. Charles Denison enumerates in the above mentioned article the different therapeutic products obtained from cultures of tubercle bacilli: the tuberculin Koch, the tuberculocidin and antiphthisin (Klebs). As No. 4 he gives " tuberculinum purificatum, which name Dr. Karl v. Ruck of Asheville has given to his manufacture of practically the same preparation." In a footnote the manner of preparation of the last is given, absolutely identical with the method published by me in 1894 for the preparation of tuberculocidin.As Dr. von Ruck, so far as I know, has never published the formula of his "tuberculinum purificatum," I can not say if Dr. Denison is in error or if Dr. von Ruck has brought on the market a preparation the same as tuberculocidin, simply using another name. Probably the first suggestion is the correct one, but the profession should be enlightened on this

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