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March 28, 1891


JAMA. 1891;XVI(13):452-453. doi:10.1001/jama.1891.02410650020004

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The analogy, in many respects, of the malignant tumors to those infective diseases, such as tuberculosis and leprosy, which have been shown to be due to the presence of microörganisms, has naturally suggested to pathologists the possibility of a similar cause, and in 1887 Scheuerlen, published an account of a bacillus which he had found in cancers, and which he believed to be the materies morbi. Similar observations have since been published by others, but his views do not seem to have met with very wide acceptance. More recently, attention has been called to other bodies occurring in cancerous tumors, which have been thought to belong to the lowest order of animal life. Darier, in 1889, described a parasite occurring in Paget's disease of the nipple, which he believed to be a coccidium—a member of the order of sporozoa. Albarran, Thoma, Wickham and Sjobring have since then reported observations of

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