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April 22, 1905


JAMA. 1905;XLIV(16):1287. doi:10.1001/jama.1905.02500430051011

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It is possible that there are yet some who doubt the existence of rabies in man as a disease entity, and there may also be some who are still skeptical as to the utility of Pasteur's method of inoculation by means of attenuated virus obtained from the spinal cord of rabbits destroyed by means of a potent virus. Nevertheless, this method of treatment has demonstrated its efficacy and has been adopted, and institutes for its application have been established, in all civilized countries. It must be borne in mind that the treatment is not curative, but prophylactic, and that its success is the greater and the. more certain the earlier it is instituted in the long period of incubation following the infecting wound, the object being to establish immunity before the development of the symptoms of the disease proper. It has been shown that when the treatment has been begun

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