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Article
April 29, 1905

THE RELATION OF THE HYPOPHYSIS CEREBRI TO ACROMEGALY.

JAMA. 1905;XLIV(17):1371. doi:10.1001/jama.1905.02500440047006
Abstract

There is no aspect of modern medicine more fascinating than that which deals with those glands which possess a so-called internal secretion. While the physiology of some of these structures is still incomplete, that of others is fairly clear, and the field is one in which pathologic lesions with the concurrent alterations in function may well serve as aids in clearing up obscure physiologic questions. In the case of the thyroid gland, and to a lesser extent in the case of the adrenals, physiology has been aided both by pathology and by experimentation, but in the case of the hypophysis cerebri experimentation is extremely difficult, on account of the anatomic situation of the gland, and we must rely largely on clinical and pathologic data to furnish us with physiologic facts.

The question of the function of the hypophysis cerebri or pituitary body has been investigated to some extent by observing

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