The desirability of an anesthetic that would obviate the general objections pertaining to chloroform and ether in operation on tonsils and adenoids has been the source of much research. The chief objection to chloroform lies in its danger; bromid of ethyl has scarcely attained any greater confidence; ether, while reasonably safe, is so prolonged in its effects as to be inconvenient for this purpose. Nitrous oxid alone has been employed by a few operators, notably at the Central London Throat Hospital, but the available operating period from a single administration is almost too brief for the satisfactory removal of both the tonsils and adenoids. Experience has proven this anesthetic, however, to be safer than any other and to possess the advantage of a rapid revival of the patient; therefore following Gardner, Hunt and Hewitt of England, and Van Arsdale of New York, we have sought to modify the action of
CASSELBERRY WE, MENGE F. TONSIL AND ADENOID OPERATIONS UNDER ANESTHESIA BY NITROUS OXID, AND NITROUS OXID AND OXYGEN: A PRELIMINARY REPORT. JAMA. 1898;XXX(10):547–551. doi:10.1001/jama.1898.72440620035001m
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