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May 6, 1905


Author Affiliations

President of the New York Academy of Medicine; Professor of Nervous Diseases, Cornell University Medical College; Visiting Physician to Bellevue Hospital. NEW YORK.

JAMA. 1905;XLIV(18):1413-1418. doi:10.1001/jama.1905.92500450001001

I wish to present what to my mind is convincing evidence that paresis, in its very earliest stages in that stage which may be called one of "præparesis," is a disease that sometimes can be arrested. This arrest may be permanent, and may be attended with so little mental defect that one may call the patient practically cured.

PARESIS, TABES AND SYPHILIS.  It is now quite generally admitted that paresis is almost always a parasyphilitic disease; that is to say, one which is due to the late and degenerative influence of a luetic poison. Paresis is also looked on as a disease which has the same relation to the brain that tabes dorsalis has to the spinal cord. This relationship, indeed, is so often and so plainly observed that it can be considered a proved clinical and pathologic fact. We find for example, in from 5 to