Within a few months after Koch introduced tuberculin to the world in 1900, the treatment of tuberculosis by means of this new remedy came into general disrepute, largely because it was used in unsuitable cases and in an improper manner. Koch had limited the proper use of tuberculin in pulmonary tuberculosis to the early stages of the disease. The remedy, however, was employed in advanced cases and in too large doses; it was administered to patients with elevated temperature, and the dose was often increased instead of reduced when fever followed the injection.
We made editorial comment1 on the remarkably satisfactory results obtained by Goetsch in the treatment of tuberculosis with tuberculin. Goetsch's article was fully abstracted in the following number.2 In a discussion on the therapeutic value of tuberculin in human tuberculosis at the British Congress on Tuberculosis3 in London in July, 1901, the consensus of
TUBERCULIN. JAMA. 1902;XXXIX(7):376–377. doi:10.1001/jama.1902.02480330030004
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