As a preface to the short report of the result of the ophthalmoscopic examination of Dr. Preston's cases, I should like to state that it is but recently that attention has been attracted to those changes of the retinal arteries as are found in general arterio-sclerosis. A few years ago Ole Bull described several cases of disease in the retinal arteries, and showed how this was the cause of symptoms frequently ascribed to embolism. Raehlmann made an exceedingly careful study of the relation between general and retinal arterio sclerosis, besides collecting a few scattered cases in literature. He examined ninety cases of general arterio-sclerosis and found that in most cases the retinal arteries were narrow and tortuous, that 19 per cent, showed whitish margins along the retinal arteries, that 21 per cent, presented localized narrowings in their course, but that retinal aneurisms are very rare. Confining ourselves to these signs
FRIEDENWALD H. REPORT ON THE OPHTHALMOSCOPIC EXAMINATION OF DR. PRESTON'S CASES OF ARTERIO-SCLEROSIS. JAMA. 1891;XVI(18):622–623. doi:10.1001/jama.1891.02410700010002a
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