Primary carcinoma of the bile duct is a comparatively rare condition. In view of the increasing interest which the region of the gall-bladder is attracting, now that it has been invaded by the surgeon, such forms of carcinoma, even though rare, acquire great practical importance. And it seems that when the question is subjected to accurate study the cases of carcinoma' of the choledochus may not be so infrequent and negliable as thought at first sight. The subject has recently been discussed by several writers, among them Miodowski1, who reports four original cases from the Pathological Institute at Breslau. In these four cases the tumor occurred at the duodenal end in one, at the upper end of the choledochus in two, and in the fourth case it was situated 1 cm. above the papilla duodenalis. Added to thirty-seven cases collected from the literature, Miodowski has in all forty-one cases
PRIMARY CARCINOMA OF THE COMMON BILE DUCT.. JAMA. 1902;XXXIX(8):434. doi:10.1001/jama.1902.02480340028004
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