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May 13, 1905


Author Affiliations

Professor of Practice of Medicine and Clinical Medicine, Toledo Medical College; Medical Department, Toledo University; Attending Physician St. Vincent's Hospital. TOLEDO, OHIO.

JAMA. 1905;XLIV(19):1518-1519. doi:10.1001/jama.1905.92500460023002c

While brain hemorrhage is not of common occurrence, it happens with sufficient frequency to make its discussion of more than passing interest to the general practitioner. In this paper I shall take into consideration only those cases which are the result of degeneration of the arterial tunics.

Degenerative changes in the coats of the blood vessels were noticed and commented on in the early days of medicine by Lobstein, who gave it the name by which it has since been known—arteriosclerosis. Morgagni and Senac also speak of it. To Rokitansky and Virchow and, more recently, to Thoma we are indebted for a thorough investigation of the nature of the process, which I shall not take the time to discuss. I shall assume that the pathologic changes in arteriosclerosis and atheroma are practically the same—differing only in degree. In the small arteries of the brain substance we find minute aneurismal pouches caused by the gradual giving way of the diseased coats.