In ophthalmic practice three disease manifestations are encountered to which the name "keratitis punctata" has been applied. Two of these are affections of the cornea, the third is not; that is to say, the primary lesion is not corneal. They are as follows: (a) keratitis superficialis punctata, in which, in general terms, numerous small punctiform or linear spots appear below Bowman's membrane, the overlying cornea being slightly hazy and the epithelium a little elevated; (b) keratitis punctata vera or syphilitica of Mauthner, in which circumscribed pinhead-sized, grayish spots appear in the parenchyma of the cornea, and, moreover, in its various layers; the iris is not involved. Constitutional syphilis is the etiologic factor. To distinguish it from the preceding manifestations Fuchs suggests the name "keratitis punctata profunda." (c) Keratitis punctata, in which a notable manifestation consists of a precipitate of opaque dots on the posterior elastic lamina of the cornea, generally
DE SCHWEINITZ GE. CONCERNING THE SYMPTOMATOLOGY AND ETIOLOGY OF CERTAIN TYPES OF UVEITIS.. JAMA. 1902;XXXIX(12):676–683. doi:10.1001/jama.1902.52480380012002
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