There are two forms of cancer of the uterus which we must consider. The more frequent form arises in the cervix of the uterus and grows more rapidly than the other form and sooner invades, by extension or metastases, the neighboring parts. On this account the diagnosis usually has not been made until after the growth has extended beyond the uterus, and, therefore, the operative treatment of this condition has been most unsatisfactory. On the other hand, the form of growth which arises in the fundus of the uterus is much rarer, grows more slowly, and remains restricted to the uterus for a much longer time. For these reasons the diagnosis is made earlier in the course of the disease and the operative treatment of cancer of the fundus is attended with a lower primary mortality and a much higher percentage of cures. In this communication I wish to refer especially to carcinoma of the uterine cervix, and, unless otherwise stated, that will be the form understood throughout the paper.
SAMPSON JA. THE IMPORTANCE OF AN EARLY DIAGNOSIS IN CANCER OF THE UTERUS.. JAMA. 1905;XLIV(20):1586–1593. doi:10.1001/jama.1905.92500470014001c
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