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September 20, 1902


JAMA. 1902;XXXIX(12):706. doi:10.1001/jama.1902.02480380042010

There occur in various parts of the body peculiar cells, often aggregated into small nodules, which for some time have attracted much attention, notably from histologists. These cells are characterized especially by the fact that they assume a brown color in solutions of chromic acid and its salts. These structures occur mostly in the regions through which passes the sympathetic nervous system, and in many cases they are connected with the sympathetic nerves. They differ from sympathetic ganglia as ordinarily understood because of the preponderance of cellular elements. The so-called carotid gland and the medullary substance of the adrenals consist, to a large extent at least, of chromophile cells.

In a recent article Alfred Kohn1 gives these mysterious cells and organs a comprehensive consideration, reviewing their occurrence in various parts of the body in different kinds of mammals, reptiles, birds, etc., in all of which they occur with marked