Among all the difficulties which have beset the subject of the proper use of drugs in disease, and there have been many, as we all know, it can not be doubted that the factor of greatest importance has been the employment of remedies by physicians without their having a correct conception, and sometimes no conception at all, of the pathological process underlying the condition which is to be relieved. This depends on the fact that many practitioners lack preliminary training, not only in morbid anatomy and morbid physiology or pathology, but also fail to study the possible effect of well-known drugs in abnormal states. The employment of certain remedies in disease has cast discredit on therapeutics by their abuse, while many physicians who have carefully studied diseased organs become so saturated, so to speak, with the seriousness of the lesions which they find that they scoff at the thought that
HARE HA. THE EMPLOYMENT OF DIGITALIS AND ACONITE IN THE TREATMENT OF CARDIAC DISEASE.. JAMA. 1902;XXXIX(13):764–766. doi:10.1001/jama.1902.52480390030002d
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