Comparatively little work has been done in the last ten years on the scientific investigation of cystitis. Some, however, has been done which is very valuable, and from it I shall take the liberty of drawing very freely.
The etiology of cystitis is essentially a bacteriological problem. The germs most frequently found are, in order of frequency, colon bacillus, streptococcus, staphylococcus in several species, typhoid bacillus, gonococcus of Neisser, proteus vulgaris and the tubercle bacillus. The fermentation of the urine has been shown by Melchior and Muller to be rather a result of infection than a cause of cystitis, certain germs producing ammonium carbonate from urea, thus converting the urine into an ammoniacal substance, giving an alkaline reaction. The chief germs which do so are the micrococcus of urea, species of the pyogenic germs, and occasionally the colon bacillus and Proteus vulgaris. It will be found in a goodly
STOKES AC. ETIOLOGY AND TREATMENT OF CHRONIC CYSTITIS. JAMA. 1902;XXXIX(13):772–773. doi:10.1001/jama.1902.52480390038002h
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