[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
September 27, 1902


Author Affiliations

Professor Genito-Urinary Surgery, Medical Department, University of Nebraska. OMAHA.

JAMA. 1902;XXXIX(13):772-773. doi:10.1001/jama.1902.52480390038002h

Comparatively little work has been done in the last ten years on the scientific investigation of cystitis. Some, however, has been done which is very valuable, and from it I shall take the liberty of drawing very freely.

ETIOLOGY.  The etiology of cystitis is essentially a bacteriological problem. The germs most frequently found are, in order of frequency, colon bacillus, streptococcus, staphylococcus in several species, typhoid bacillus, gonococcus of Neisser, proteus vulgaris and the tubercle bacillus. The fermentation of the urine has been shown by Melchior and Muller to be rather a result of infection than a cause of cystitis, certain germs producing ammonium carbonate from urea, thus converting the urine into an ammoniacal substance, giving an alkaline reaction. The chief germs which do so are the micrococcus of urea, species of the pyogenic germs, and occasionally the colon bacillus and Proteus vulgaris. It will be found in a goodly