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November 8, 1902


JAMA. 1902;XXXIX(19):1158-1160. doi:10.1001/jama.1902.52480450008002a

Next to glioma of the retina primary sarcoma of the choroid is the most frequent intra-ocular growth. Metastatic, on the contrary, is extremely rare and has only been authentically reported by Shiess-Gemusens, Pflüger and De Schweinitz. In Norris and Oliver's System of Diseases of the Eye (1898), Hill Griffith, in his article on sarcoma of the choroid says: "Sarcoma of the choroid is always primary, always single and generally more or less deeply pigmented; it never affects both eyes." We are all familiar with the saying of Virchow that in those organs which show a special disposition to nurture new growths, metastatic foci are seldom seen. Thos. Axenfeld, in a review of "Tumors of the Eye," published in 1897, says: "We know of only two positive cases of metastatic uveal sarcoma; those of Pflüger and Shies-Gemusens and Roth." In Pflüger's case one eye became blind while in the other a