After an anesthetic has been demonstrated to be effective, the next absorbing and vital question is its safety. On this score the brute force alone of numbers is telling, and I hope, therefore, in this narrative, to carry conviction in this direction on the basis of one thousand personally conducted narcoses with ethyl chlorid, and some collected statistics. These thousand narcoses were all conducted with ethyl chlorid sold under the trade name of "Kelene" and a mask of my own devising, described in previous communications.1 For the present I must insist on the use of the above variety of ethyl chlorid, since other preparations marketed in this country, ordinarily intended for local anesthesia by freezing, are impure, containing methyl chlorid to facilitate evaporation. Furthermore, it happens that the above mentioned preparation of ethyl chlorid is the only one thus far provided with a suitable automatic cutoff to control the
WARE MW. ONE THOUSAND PERSONALLY CONDUCTED CASES OF ETHYL CHLORID NARCOSIS. JAMA. 1902;XXXIX(19):1160–1162. doi:10.1001/jama.1902.52480450010002b
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