A review of the large and increasing statistics of infantile palsies applying for treatment in the metropolitan clinics of children's and nervous diseases shows plainly that the cause and prophylaxis of these disorders are in need of more minute study. The morbid anatomy and the manner of production of the spinal type is fortunately well known from the more recent work of Semerling, Goldscheider, Medin, Strümpel and Zupper, but its minute pathology and pathogenesis are still in doubt.
A question still under discussion is, are they primarily parenchymatous or vascular in their inception? The general trend of modern research is in favor of the latter theory, while the secondary changes are considered to be interstitial and parenchymatous. Opinions appear about equally divided between the theories of the autotoxic and organismal cause of the primary lesion, but the force of its epidemic occurrence is in favor of the latter.
THE STUDY OF PALSIES.. JAMA. 1902;XXXIX(23):1463. doi:10.1001/jama.1902.02480490035007
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