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August 11, 1900


JAMA. 1900;XXXV(6):358-359. doi:10.1001/jama.1900.02460320028006

Although the exact mechanism of the development of glycosuria is not known, it has become perfectly well recognized that the manifestation is merely a symptom that may be associated with any one of a number of conditions. It has perhaps been longest and best known as one of the phenomena of diabetes mellitus, and too commonly the two have been considered identical. Whether or not there may be a grave diabetes without glycosuria, as there may be a marked glycosuria without diabetes, is a question for future investigation to decide. Perhaps, too, there is a more intimate relation between diabetes mellitus and diabetes insipidus than is generally acknowledged Sugar is not found in the urine with great frequency under ordinary conditions, either in disease or in health, although in some persons it may readily appear upon excessive indulgence in saccharine or amylaceous articles of food. Saundby1 recently in a