The chief function of the nervous system, beside its special function, is that of regulating growth and repair. This function, as Marinesco points out, resides even in the neuron or nerve unit. While this function of regulating growth and repair is often connected with control of the vasomotor system, still, as Collins remarks, there are trophoneuroses in which there are no appreciable vasomotor disturbances, and there are any amount of vasomotor disturbances which are in no sense connected with disturbances of nutrition. The nerves regulating growth and repair are called trophic nerves, and the conditions produced by anomalies of their action are, as already stated, called trophoneuroses. It was in the domain of bone growth that anomalies of the function of the trophic nerves were first observed. Brown-Séquard pointed out certain anomalies in the joints of locomotor ataxics; later similar disturbances were observed in the jaws of patients with this
KIERNAN JG. NEUROTIC AFFECTIONS OF INTERSTITIAL GINGIVITIS. JAMA. 1900;XXXV(7):418–419. doi:10.1001/jama.1900.24620330022001g
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