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September 15, 1900


Author Affiliations

Professor of the Diseases of Metabolism, College of Physicians and Surgeons, St. Louis; Visiting Physician, New York Red Cross Hospital; Attending Physician, St. Elizabeth's Hospital; Member American Medical Association; Member American Chemical Society; Fellow New York State Medical Association, etc. NEW YORK CITY.

JAMA. 1900;XXXV(11):679-683. doi:10.1001/jama.1900.24620370021001j

Dextrose, in insignificant traces a constituent of almost every normal urine, can be readily demonstrated in the renal excretion, provided it occurs in sufficient amounts. The moment, however, that urinary grape-sugar is detected by the more commonly employed methods, it indicates a deviation from the normal systemic state. Thus, in glycosuria, no specific pathologic element makes its appearance, but a regular constituent of excessively increased quantity. While, as a rule, glucose can be positively identified in urines containing 0.5 per cent. or more of it, great difficulty in this respect is often experienced when smaller amounts are present.

Glycosuria, a well-defined condition, resulting from or concurring with some systemic anomaly, is most always recognized by the painstaking physician; yet, certain systemic occurrences—physiologic or pathologic—may be erroneously diagnosed as glycosuria, when, as a matter of fact, grape-sugar in appreciable quantities was never discharged by the urine. Coinciding with pseudoglycosuria, there may