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Article
October 27, 1900

CHANGES IN THE MOTOR GANGLION-CELLS ASSOCIATED WITH PERIPHERAL NEURITIS.

JAMA. 1900;XXXV(17):1091-1092. doi:10.1001/jama.1900.02460430027004
Abstract

Whether or not the conception of the neuron as applied to the nervous system can be accepted without qualification in its present form, there is no doubt that it has been a great help in clarifying our physiologic and pathologic notions in this field of observation. Viewing the nerve-cell and its processes as one continuous whole, it can be readily understood how a lesion in any part of it will give rise to similar clinical manifestations. Further, as the nutrition of the cell is dependent on the integrity of the body, through its nucleus, it must be evident that the most remote part will be the most susceptible to degenerative changes. Disease of the cell will necessarily be followed by disease in its processes, but it has not been sufficiently appreciated that disease in the latter may be attended with changes in the former. It has been observed that sometimes

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