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November 10, 1900


JAMA. 1900;XXXV(19):1213-1214. doi:10.1001/jama.1900.24620450029001j

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The following three cases of bubonic plague have occurred in San Francisco since the last report on this subject by The Journal:

Case 16.  —Lea Do Hen, aged 50, Mongolian, cigarmaker, had lived in California 28 years. His residence was 710½ Dupont street. Patient died Oct. 5, at 10 p. m.Examination of the body revealed a large bubo in the right inguino-femoral region. Incision disclosed a lymph node about the size of an egg, surrounding which the tissues were filled with a chocolate-colored fluid. The cut surface of the gland was very dark, purple and mottled, but substance fairly firm. A microscopical examination showed numerous bipolar-staining bacilli, decolorizing by Gram's method. Two guinea-pigs were inoculated with a glandular emulsion on Oct. 7.One of the pigs lived four and one-half days after inoculation. On examination there was found a large area of coagulation necrosis surrounding the point of inoculation

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