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March 12, 1892


JAMA. 1892;XVIII(11):329-330. doi:10.1001/jama.1892.02411150019003

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A pernicious form of osseous disease is the subject of a Vienna clinical prelection by Professor Nothnagel, given in full in two recent numbers of the Press and Circular. The changes of structure discovered by autopsy, were unusual in extent, having invaded the entire skeleton and obliterated the medulla of the bones by a perversion of that force or those forces whose "elaboration should constantly proceed in the healthy hæmatic organs." The case was that of a male, aged twenty-four years, hitherto healthy, with good family history, and living in fairly hygienic surroundings. He was first a "Schwizer," or cowherd, and later a soldier in a small Tyrol barracks. His attack dates from eighteen months ago, with fever and pain in the breast and limbs, without appreciable cause. The temperature was not recorded accurately until a month before death. Sweating was profuse at the outset of the attack, and also

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