a. In illustration of secondary diseases produced in a mechanical manner may be quoted the remote pressure effects of new growths, aneurysms or tumefactions of any kind. If the pressure is exerted upon nerves it leads to their atrophy; if it involves tubular organs like the intestines or the ureter it is followed by the consequences of their obliteration. Another mechanical instance of secondary affection is the strangulation of the intestines by peritoneal adhesions. Stenosis of the nasal passage can cause mechanically hypertrophie changes in the nasopharynx and Eustachian tubes, which often become complicated by subsequent infections. Interference of respiration on account of enlarged pharyngeal or faucial tonsils may lead to deformity of the thorax and possibly even spinal curvature. A secondary disease of mechanical origin is also furnished by the detachment of a clot within the circulatory system and the subsequent embolism of a terminal artery. Under
GRADLE H. LECTURES ON GENERAL ETIOLOGY.Delivered at the Chicago Medical College. JAMA. 1892;XVIII(17):519–522. doi:10.1001/jama.1892.02411210013001d
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