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April 30, 1892

The Inebriate Diathesis.

JAMA. 1892;XVIII(18):560-562. doi:10.1001/jama.1892.02411220022003

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To the Editor of the Journal of the American Medical Association:  An incident in the history of the workings of the inebriate diathesis and its origin and treatment, has come to my knowledge, which seems to me both interesting and instructive. To fully appreciate its significance, I will, with your permission, introduce my account, with some prefactory observations bearing upon the principles to be derived from it, and the lessons to be taught by it.Neuro-pathologists agree that constitutional diseases of the nervous system, are prone to change their forms. Their aspects, symptoms, their physical manifestations, are indeed liable to such radical variations in appearance, that they are known as distinct diseases and bear different names. And these changes in form occur, not through force of heredity alone, but sometimes they take place even in the life and experiences of a single individual. I have witnessed striking instances of this

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