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June 4, 1892

METHYL VIOLET AND BLUE.Read before the Ohio State Medical Society, Cincinnati, May G, 1892.

Author Affiliations

OF CINCINNATI. O.

JAMA. 1892;XVIII(23):710-715. doi:10.1001/jama.1892.02411270018001f

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Abstract

As I am able in the short time allotted to each paper to present but part of my subject, I will ask permission to read a short résumé of the observations made by others, and then report my own cases in what time is left.

The first general knowledge of the aniline preparations came to us through the studies of the bacteriologists. As is now well known, the tubercle bacillus was discovered and declared by Koch in 1882 with the aid of methylene blue. The next reference was the claim by Kremiansky, 1888, to destroy this bacillus by causing patients to inhale this coloring matter. Then J. Stilling, Professor of the University of Strasburg, 1890, made the discovery that certain aniline dyes exercise a destructive effect upon bacteria in the living organism, and especially upon suppurating surfaces, hence he gave one of them the name pyoktanin. from πυον, pus, and

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