The number of cases of this form of cutaneous infection is increasing constantly. Up to this time it seems that typical blastomycetic dermatitis has been recognized and studied by Americans solely. There are now about twenty recorded cases in which the diagnosis is satisfactorily established by the study of the microscopic character of the lesions and the characteristic, budding, doubly-contoured organisms usually present in the little abscesses that form such a prominent feature of the clinical as well as the anatomical picture. And yet it is to be remembered that absolute demonstration of the etiological rôle of the organisms is still wanting. No one has produced blastomycetic dermatitis by experimental inoculation of human beings with pure cultures, and in the ordinary laboratory animals the convincing cutaneous lesions do not follow local infection. But the clinical picture, the histopathology, and the presence of the organisms, which are often easily isolated, at
BLASTOMYCETIC DERMATITIS.. JAMA. 1901;XXXVI(2):112. doi:10.1001/jama.1901.02470020040004
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