While we have no direct specific remedy for typhoid fever, and no knowledge of any drug that destroys the bacillus of this disease, the proper management of the gastrointestinal system, and especially during the early period, will prove of decided advantage. Among the principal objects met in this way is the preservation of the strength and vitality of the patient, thus probably inhibiting the virulence of the bacilli and their toxins, as well as that of some of the intestinal organisms which are otherwise harmless. Moreover, we can diminish somewhat the amount of intestinal toxins, and hence to an equal extent their absorption into the general system. The frequency of certain symptoms and complications—meteorism, vomiting, diarrhea—which are so very prone to manifest themselves if the prima via be neglected, may also be lessened.
Before discussing the usefulness of drugs in this condition, which I grant are subsidiary in importance to
ANDERS JM. TREATMENT OF THE GASTROINTESTINAL SYMPTOMS IN TYPHOID FEVER.. JAMA. 1901;XXXVI(4):247–250. doi:10.1001/jama.1901.52470040025001i
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