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That the eye should be subject to rheumatic disease does not seem strange when we remember that its principal protective coat is a dense fibrous structure, the sclerotic; that it contains within it the delicate muscular fibers of the iris and ciliary body, and externally the muscular bands which move it about; that it is very vascular, one coat alone, the choroid, being largely made up of blood-vessels. The wonder is that the eye does not suffer more from a disease as prevalent as rheumatism and one which shows such a predilection for fibrous, muscular, and vascular structures.
It is not the object of this paper to discuss the subject of rheumatism in general. Suffice it to say that many observers believe it to be, like gout, caused by uric acid, a product of inefficient proteid metabolism; others by lactic acid, a fermentation product of the hydrocarbons. The researches of
WOODRUFF HW. RHEUMATIC DISEASES OF THE EYE.. JAMA. 1901;XXXVI(6):363–364. doi:10.1001/jama.1901.52470060007001b
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