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February 18, 1893

COMPARISON OF MARKET FLUID EXTRACTS AND THEIR RELATION TO FIFTY PER CENT. TINCTURES.Read in the Section of Materia Medica and Pharmacy, at the Forty-third Annual Meeting of the American Medical Association, held at Detroit, Mich., June, 1892.

JAMA. 1893;XX(7):177-180. doi:10.1001/jama.1893.02420340011001b

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The question of the variability of fluid extracts as made from different lots of drug, by different manipulators, has often been discussed, and the suggestion has been made that if substituted by 50 per cent. tinctures, retail pharmacists could profitably make their own products.

It has even been asserted that 50 per cent. tinctures would average to be as strong as many market fluid extracts.

To arrive at an impartial verdict we have kept the record of 300 lots of fluid extract of dandelion U. S. P., and 250 lots of fluid extract of wild cherry U. S. P., made by as many operators from four uniform lots of drug.

The dry extractive from the dandelion was 26, 28, 30 and 38 per cent.

The range obtained by the 300 students was from 8.5 per cent. to 31 per cent.

The glycerin extractive from the wild cherry was 27, 28.8,

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