It seems probable that diabetes has long been recognized, although the presence of sugar in the urine, from its sweetish taste, was first detected in the seventeenth century, and it was not until the eighteenth that glucose was isolated. Then followed a careful description of the disease, with the recommendation of an animal diet and exclusion of vegetable food in treatment. Scientific study of the etiology, nature and treatment of diabetes, was, however, not begun before the middle of the nineteenth century, but since then few diseases have had more attention devoted to them, both clinically and experimentally. In an interesting communication, von Noorden1 discusses some as yet unsettled questions in this connection, and points out the lines along which scientific investigation may profitably be directed. Quite apart from increased thoroughness of clinical study, there is scarcely room for doubt of the increased morbidity and mortality of diabetes.
DIABETES MELLITUS.. JAMA. 1901;XXXVI(9):574–575. doi:10.1001/jama.1901.02470090038003
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